Semaglutide mimics GLP-1, an incretin hormone that plays a role in appetite and digestion. It’s thought to work in a few different ways to help you lose weight. These include:

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• Slows the movement of food out of your stomach (gastric emptying)

• Targets areas of the brain that help regulate appetite and fullness

• Reduces cravings for certain foods, such as salty snacks or sweets

 

Certain semaglutide effects, such as slowed gastric emptying, may lessen over time. Other semaglutide effects, such as appetite reduction, only last as long as you’re using the medication. Before starting semaglutide for weight loss, it’s important to discuss the potential benefits and risk of treatment with your healthcare team. That’s because semaglutide isn’t right for everyone. It’s also a long-term commitment since rebound weight gain is possible if you stop using it.